You will be doing that with them all, if you dont want to mess with it then leave it standard lol
use the ecu that has the most back up for you personally, but all i can say is ive used MS on four of my daily drivers, over six years and there was only one small failure that was self inflicted. (the good thing about MS is you can replace components/fix it yourself, cheaply if you blow something up with stupidity/inexperience)