I can't wait to get the runflats off my old dears E90 M-sport... the ride is beyond unacceptable on poor surfaces, it actually annoys you if it lasts for any length of time. That said, it's on the 19" wheels with the rear tyres running a 30-profile tyre so even with softer tyrewalls it's hardly going to be comfy but any improvement will be welcomed.
The tyre shop/supplier that I use has told me that he wouldn't recommend running non-RF and RF tyres at the same time though... not sure exactly why, he explained it to me, but that was a couple of years ago now and I've forgotten.
Cheers,
Grant