No, because the 4x4 intercooler doesn't quite fit between the upper fan shroud flanges. It's slightly wider, deeper, and taller than the 2wd intercooler.
Even on the standard Ford radiator, a small piece of metal needs to be removed from the flanges to allow the bigger 4x4 intercooler to fit.
I couldn't bring myself to cut into my Airtec rad, so I resorted to using the original 2wd cooler.
I drew this - it's not to scale or anything, but illustrates the issue: