So if you murdered someone at 35,000 ft in a Boeing over International waters you could get away with it????
I'm pretty sure the plod will be waiting for you when you landed.
As with the spaceship 2 I'm sure it would take on the same jurisdiction as its country of origin.
I'm pretty sure If the aircraft is in international airspace or just space

then the law of the country where the aircraft is registered applies.
maybe