yes, ive seen the effects on quite a few people,we used to invite them in to talk to our students, including one guy who couldnt breathe without a machine. he also thought it would be ok this time, then just once more,and now his life is fooked.
it just aint worth the risk imo, who knows if you guys are taking risks it may be you in 10 years! work related asthma is a nasty nasty thing.
i can certainly feel the effects of using 2k for 7-8 years, which is why i stopped using it