it can but not something i have tried........... i had 283 rwd discs with granny cos calipers and was very effective, but others have tried and it may require a little fettling of the caliper...........
scorpio cosworth discs are 4 stud, the right size 278 and the offset is closer, not sure with the 4x4cos calipers though,

tbh i haven't noticed any real difference with a car with 4x4 cos brakes than a granny cos setup.................... saves pennies as well........