If you ever have a problem with a person how do you tackle it?

I'm normally misunderstood, what i say is often taken the wrong way. I dunno why-but thats the way it is. Maybe i'm not so elegant in expressing how i feel?
A few people in the past have made snide remarks about friends. Others take them to one side to talk about it. Many i know will argue to the death-well almost.

Normally i haven't a problem with anyone unless they make it obivious they don't like me for what ever reason.

How do you deal with people who don't like you but who you see often? (Through work/family)