The cam marks are only for a std, un touched engine, but even then, they arn't that accurate.
so as soon as its been skimmed, or de comp plate fitted, your not be able to get the mark spot on.
So the cam needs dialing up with a dial gauge and a adjustable vernier to get it spot on.
Then the ign timing needs setting @ 900 rpm, @ 12' static timing, (or if chipped, what ever the chip manufacture says)
But ideally needs setting up with Det cans whilst on boost.