Pee Vee
Tell me about it. Well component wise, downside is excess cylinder pressure - so has to be studded with wrc gasket etc.
And a good mapper (Stu/Harvey/Karl etc) can make a low comp engine as enjoyable as a high comp one if its specced ad set up properly. And it'll last longer.
Remember, most high comp engines are rebuilt regularly as they are mostly used in competition. Though I'm sure there are a few who will disagree.