well Royal Bank of Scotland use Sophos but thats shit as well.. everyone i work with use AVG or Mcafee, i stopped using McAfee as they dont update as often as AVG..

oh and im a very HUGE downloader!!!!.. also run my own webserver from home and have 1.5terrabytes of storage on it and i only have my hadrware firewall on that and AVG and MS antispyware on it.. no problems at all.. youll only get spyware from shit software, use bittorrent to download and you wont get virus/spyware