I've never heard of anyone having any ill effects but it is a relatively new product. Its not a banned substance so the authorities cant deem it that bad.
Full instructions for loading up etc will be on the packet/tub but as said you hould load up over a 5 day coare and then maintain levels for 4-6 weeks before coming off again for a 4 week break.
I have also heard raving reports about the liquid creatine if you can get hold of it. Supposed to go straight into your system and is apparently more potent? Personally I would just go for 100% pure creatine if I were you and avoid the flavoured type stuff as I didn't find them as good. Too watered down.