Hmm, Id say probably not a massive amount of difference in terms of wear etc.
If it was even remotely possible at work, would be great to stick a fresh engine on one of the dynos, run it for a week and strip to examine it, however not really possible

.
Id not have thought theres too much wear, i'd imagine really it'd just be stressed between the centre line of the crankshaft and the big end, and if this doesnt come near any kind of structural limit anyway (ie, 95, 96, 95, 96 etc over 4 pots - yet the materal can take 200.). The crankshaft should always be floating on oil anyway, so shouldent get much extra bearing wear, as the crank always has a power stroke in a different place along it anyway.
Hmmm....as you said mate, any views, this is mine as a first year mech engineering student, so, could be totally wrong.
Would be great to hear what Karl has to say as an engine designer, as opposed to just a tuner, someone who has worked on dynos doing R&D (ie, at Jag, rather than 600bhp R&D that say Sheady might do).